“Biofilms: role in health and disease, recalcitrance and in vitro modelling” By Dr Andrew McBain

Date: Wednesday, 27th May 2015 (click for Google Calendar entry)
Time: 8.15 pm – 9.45 pm
Venue: Inorganic Chemistry Lecture Theatre, South Parks Road

Please RSVP at our Facebook event page so that we can better estimate attendance numbers for that day!



Talk abstract:
Microorganisms often grow as sessile communities in association with surfaces. The unique physiology of such biofilms is important in many aspects of life. To our benefit, they may confer colonisation resistance to infection, assist the absorption of nutrients from the bowel and contribute to biodegradation and some industrial processes. Biofilms are however often associated with problems which include biofouling and persistent infections where they are characterised by recalcitrance towards antimicrobials. This talk will present an overview of biofilms, considering what is understood about the mechanisms underlying recalcitrance, and will outline approaches that have been developed over the past 30 years or to study them in the laboratory (principally in vitro models).

Speaker Bio:
After graduating from the University of Liverpool in 1993, Andrew moved to the University of Cambridge to study for a Ph.D. in medical microbial ecology with the MRC at Addenbrooke’s Hospital. For the last twelve years, his research at Manchester has focused on the responses of biofilms to antimicrobial treatments and the interaction of microorganisms colonising the skin, nasopharynx, oral cavity and intestine with the human host in health and disease. His research group is interested in bacterial physiology and ecology as it relates to human health and disease and to clinical/environmental persistence. A central theme is the in vitro modelling and characterisation of microbial communities and well as the interactions between bacteria and the host.

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